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Kantarjian et al53 assessed the efficacy and safety of dasatinib, as compared with imatinib, for the initial-line therapy of CML-CP. 5 hundred and nineteen clients with recently diagnosed CML-CP were randomly assigned to obtain dasatinib at a dose of one hundred mg as soon as each day (259 individuals) or imatinib at a dose of 400 mg at the time da